Abstract:[Abstract] Objective The aim of this study was to retrospectively compare a series of patients surgically treated with ORIF or prosthesis due to isolated comminuted radial head fractures. Methods From 2015 to 2017, 52 patients with isolated comminuted fractures of the radial head (Mason Type 3) had been operated (ORIF in 26 patients, Prosthesis in 26 patients) in our hospital. Preoperative imaging examinations, including anteroposterior and lateral X-ray of the elbow, and CT and MRI examination, were performed to identify the types of fracture and concomitant injury. The system of Broberg-Morrey,and range of motion (Flexion- Extension and Supination-Pronation) was used to evaluate the clinical results. Results: Open reduction group, with an average follow-up of 28.3±5.1 months, along with other damage of 25 cases, B&M score averaged 78.0points (69.8,81.5). excellent and good rate was 19.2%;Prosthesis groups, with an average follow-up of 27.4±4.1 months, all accompanied by other damage, B&M score averaged 91.0points (85.0,96.0), excellent and good rate was 100%. Two groups were no significant differences in concomitant injury, gender, age, and follow-up time. And We found a statistically significant difference between the ORIF and resection groups regarding the clinical outcomes. Conclusion: In Mason type III due to difficulty in achieving anatomical reduction results were not good with reconstruction when compared with prosthesis.