Abstract:Degenerative cervical disc disease, also known as cervical spondylosis, is out of commen diseases that does seriously affect people's physical health and quality of life. Anterior cervical decompression fusion (ACDF) is a classic surgical procedure for cervical spon- dylosis, however, what kind of anterior cervical internal fixation system used will have different effects on surgical outcomes. Compared with the traditional titanium plate combined with cage, the new internal fixation system, zero-profile cage-plate device can significantly shorten the operation time, reduce intraoperative blood loss, reduce the incidence of postoperative dysphagia and sore throat and prevent adjacent segment degeneration. This article reviews the advantages and disadvantages of two anterior cervical internal fixation systems for ACDF in the surgical treatment of cervical spondylosis.