Abstract:[Objective] To introduce the surgical technique and preliminary clinical results of open reduction and internal fixation (OR- IF) of double- column acetabular fractures through a single lateral rectus abdominis approach. [Methods] From September 2016 to July 2019, 32 patients with double-column acetabular fractures were treated by ORIF through a single lateral rectus abdominis approach, in- cluding 14 males and 18 females, aged ranged from 21 to 72 years, with an average of (36.42±4.73) years. The acetabulum was exposed through the lateral incision of the rectus abdominis. The first and second windows were separated by the external iliac artery and vein, while the third window was the lateral iliopsoas muscle. The anterior column, quadrilateral area and posterior column were exposed, reduced and fixed by the combination of the first window and second window, while the iliac margin was exposed, reduced and fixed by the third window. The acetabular reduction was evaluated by Matta's criteria, whereas postoperative hip function was evaluated by modified Merle D 'Aubig- ne and Postle criteria. [Results] All patients had operation completed smoothly without obvious complications, and followed up from 9 to 24 months with a mean of (14.73±2.34) months. Based on Matta's criteria, quality of fracture reduction was of excellent in 21 cases, good in 7 cases, fair in 4 cases, with excellent rate of 87.5%. By the time of the latest follow-up, the clinical outcome was marked as excellent in 19 cases, good in 8 cases, fair in 4 cases and poor in 1 case with an excellent and good rate of 84.3% according to Merle D 'Aubigne and Pos- tle's criteria. [Conclusion] The lateral rectus abdominis approach has the advantages of small incision, full exposure of quadrilateral area and anterior column, as well as fixation of posterior column with screw and iliac plate under direct vision, and fewer complications.