Abstract:[Objective] To explore the significance of staged injury control and treatment for severe lower extremity damages in emer- gency. [Methods] A total of 116 patients with severe lower extremity injuries were divided into two groups according to treatment in emer- gency. Of them, 64 patients in the trial group received staged injury control and surgical treatment according to the theory of damage con- trol, while the remaining 52 patients in the control group underwent conventional emergent treatment. The rescue and lower limb function recovery were compared between the two groups. [Results] The trial group proved significantly higher rescue success rate, whereas signifi- cantly shorter emergency time, ICU days, and hospital stay than the control group (P<0.05) . At one month after emergent surgical treat- ment, the trial group had significantly higher muscle strength and flexion and extension range of motion (ROM) , whereas significantly lower incidence of knee stiffness, local swelling, local blisters and complication in total than the control group (P<0.05) . The trial group was marked significantly higher total satisfaction rate of family members than the control group (P<0.05) . [Conclusion] The use of staged injury control and surgical treatments for severe lower extremity injuries does effectively shorten the time elapsed in emergency, increase the suc- cess rate of rescue, and promote the recovery of lower extremity functions.