Abstract:[Objective] To evaluate the clinical efficacy of microscopic resection of lumbar intradural spinal tumors. [Methods] A retro- spective study was conducted on 32 patients who received microscopic resection of lumbar intradural spinal tumors in our department from April 2016 to April 2019. The clinical and imaging data were evaluated. [Results] All the patients were successfully operated without seri- ous complications, while with operative time of (135.35±28.57) min, the intraoperative bleeding of (108.2±12.95) ml, and the postoperative hospital stay of (9.01±2.05) days. At the latest follow-up lasted for (9.03±2.01) months, all of them regained muscle strength to basically normal level, without tumor recurrence or spinal deformity. The VAS and JOA scores, as well as Frankel index for neurological function im- proved significantly over time (P<0.05) . Radiographic checks showed that the tumors were resected completely in all the patients, and no tumor recurrence or spinal deformity was observed during the follow-up period, with good spinal stability and no significant degenerative changes of the involved spinal segment. [Conclusion] Microscopic resection of lumbar intradural tumors has the advantages of minimizing iatrogenic trauma and improving recovery, and does effectively restore spinal cord function.