髌骨骨巨细胞瘤1例并文献复习△

Giant cell tumor of patella: a case report and literature review

摘要:

髌骨是人体最大的籽骨，发生于髌骨的肿瘤较为少见，原发性髌骨肿瘤中良性多见，其中骨巨细胞瘤最为常见。骨巨细胞瘤多见于 20~40 岁，女性多于男性，好发于长骨的干骺端。因髌骨骨巨细胞瘤临床症状多不典型，表现为关节周围疼痛及压痛、关节活动受影响等，因此易被误诊为膝关节疾病。临床工作中诊断该病需要临床表现、影像学和病理资料三结合，治疗以外科手术为主。如何完整切除肿瘤防止复发，仍是治疗髌骨骨巨细胞瘤的重难点。笔者通过回顾性分析本院收住的 1 例髌骨骨巨细胞瘤患者的临床资料，并查阅国内外相关文献，对髌骨骨巨细胞瘤进行综述。

Abstract:

Patella is the largest sesamoid bone in human body with relatively rare occurrence of tumors, and most of the primary patel- la tumors are benign, of which giant cell tumor is the most common. Giant cell tumor of bone (GCT) is frequently seen in 20-40 years old with female more dominate than male, and the metaphysis of long bone as common site involved. Due to the atypical clinical symptoms of GCT of the patella that usually manifests as pain and tenderness around the joint and limited motion, it might be misdiagnosed as other knee disease. Clinical diagnosis of GCT of the patella requires a combination of clinical manifestations, imaging and pathological data, addi- tionally surgical operation is the main treatment for it. How to completely remove the tumor to prevent recurrence remains a difficult prob- lem in the treatment of GCT of patella. In this paper, a case of GCT of patella admitted in our hospital was reported and relevant literatures at home and abroad were reviewed.