Abstract:[Objective] To compare the clinical outcomes of suture anchor versus cannulated screw for arthroscopic fixation of anterior cruciate ligament (ACL) tibial avulsion fractures. [Methods] A retrospective study was conducted on a total of 84 patients who underwent arthroscopic reduction and internal fixation of ACL tibial avulsion fracture in our hospital from June 2012 to June 2018. According to doc- tor-patient communication, 44 patients had fracture fixed with suture anchors (SA) , whereas the remaining 40 patients were fixed with can- nulated screws (CS) . The perioperative, follow-up and imaging results were compared between the two groups. [Results] All the 84 pa- tients had operation performed successfully without vascular or nerve injury. Although the SA group consumed significantly longer opera- tion time (P<0.05) , whereas resumed walking postoperatively significant earlier than CS group (P<0.05) , there was no significant differenc- es in the other perioperative parameters between them (P>0.05) . All patients in the two groups were followed up for (25.18±4.53) months, and the SA group resumed full weight-bearing activity significantly earlier than CS group (P<0.05) . The knees stability revealed by pivot shift test and Lachman test significantly improved in both groups postoperatively compared with those preoperatively (P<0.05) , whereas which was not statistically significant between them at any matching time points (P<0.05) . The Tegner, Lysholm, and IKDC scores in- creased significantly over time in both groups (P<0.05) , which in the SA group proved significantly superior to the CS group at 3 months af- ter surgery (P<0.05) , whereas became not statistically significant at 6 months postoperatively and at the latest follow-up (P>0.05) . Radio- graphically, there was no significant difference in fracture reduction quality between the two groups (P<0.05) , but the SA group got fracture healing on images significantly earlier than the CS group (P<0.05) . In addition, there was no significant change in term of Kellgren-Law- rence grades for knee degeneration in both groups until the latest follow-up (P>0.05) . [Conclusion] Both SA and CS fixation do effectively treat ACL tibial avulsion fracture, by contrast, SA has the advantages of facilitating fracture healing and providing better early clinical out-comes over the CS.