Abstract:[Objective] To systematically evaluate the efficacy of percutaneous endoscopic transforaminal (PETD) and translaminar (PEID) approaches in the treatment of calcified lumbar disc herniation (cLDH). [Methods] From January 1973 to February 2023, PubMed, Web of science, EMSCO, CNKI, Wanfang and VIP databases were searched to collect literatures on the efficacy of PETD and PEID in the treatment of cLDH. References were screened according to inclusion and exclusion criteria, and quality assessment and data extraction were performed. Meta-analysis was performed by Revman 5.4 software. [Results] A total of 2 English literatures and 1 Chinese literature were included. PETD treated 89 cases and PEID treated 72 cases. The results of meta-analysis showed that the lower extremity VAS score and ODI score were significantly improved in the PEID group and the PETD group before treatment and at the last follow-up, and the difference was statistically significant (P<0.05); There was no significant difference between PEID and PETD groups in age, sex, disease course, lower extremity VAS score, lumbar spine dysfunction index (ODI), Modified score of postoperative good and good rate, and postoperative complications (P>0.05). [Conclusion] Both PEID and PETD can effectively treat calcified lumbar disc herniation, and there is no difference in efficacy and complication rate between the two groups.