足踝部痛风清除术的临床观察
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滨州医学院烟台附属医院

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兼具关节隔离支撑和药物长效续释功能的高强度温敏性滑动轮水凝肢的合成及生物学性能评价


Clinical observation on gout removal from the foot and ankle
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Yantai Affiliated Hospital of Binzhou Medical University

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Synthesis and biological evaluation of a high-strength temperature-sensitive sliding wheel hydrogel limb with joint isolation support and long drug sustained release function

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    摘要:

    [目的]评价手术治疗足踝部痛风的临床疗效。[方法]回顾2016年12月—2022年6月接受手术治疗的足踝部痛风患者38例;观察并比较术前、术后3个月及末次随访血尿酸水平、痛风发作频率、视觉疼痛模拟评分(visual analogue scale,VAS)评价疼痛缓解和尿酸控制情况;观察并比较术前、术后3个月及末次随访美国矫形外科足踝协会(America orthopedic Foot&Ankle Society,AOFAS)踝-后足评分患者踝关节功能;结果:38例患者随访6-12个月,纠正畸形、运动功能恢复满意,末次随访VAS评分由术前(6.3±1.1)分下降至(2.0±0.5)分,痛风发作频率由术前(3.5±0.9)次/月下降至(0.8±0.4)次/月,血尿酸水平由术前(586.8±90)μmol/L下降至(392.1±21.5)μmol/L,AOFAS评分由术前(66.1±3.7)分提高至(79.1±3.6)分(P<0.05)。[结论]手术清理足踝部痛风可显著降低并控制尿酸水平,有效缓解疼痛、改善踝关节功能,临床疗效良好。

    Abstract:

    [Objective] To evaluate the clinical efficacy of surgical treatment of foot and ankle gout. [Methods] Thirty-eight patients with gout in the foot and ankle who underwent surgical treatment from December 2016 to June 2022 were reviewed; preoperative, 3-month postoperative, and final follow-up blood uric acid levels, frequency of gouty attacks, and visual analogue scale (VAS) for evaluating pain relief and uric acid control were observed and compared; Observe and compare the ankle function of patients with American Orthopedic Foot & Ankle Society (AOFAS) ankle-hindfoot scores at preoperative, 3 months postoperative and final follow-up; results: 38 patients were followed up for 6-12 months, with satisfactory correction of deformity and recovery of motor function, and the VAS scores at the final follow-up were decreased from preoperative ( 6.3±1.1) to (2.0±0.5), the frequency of gouty attacks decreased from preoperative (3.5±0.9)/month to (0.8±0.4)/month, the blood uric acid level decreased from preoperative (586.8±90)μmol/L to (392.1±21.5)μmol/L, and the AOFAS score increased from preoperative (64.6±4.5) to (79.1±3.6) points (P<0.05). [Conclusion] Surgical cleanup of foot and ankle gout can significantly reduce and control uric acid levels, effectively relieve pain and improve ankle function, with good clinical efficacy.

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  • 收稿日期:2023-07-15
  • 最后修改日期:2023-09-28
  • 录用日期:2024-01-19
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