Abstract:[Abstract] Objective: To investigate the clinical efficacy of combined minimally invasive surgery in the treatment of invasive hemangioma of thoracic vertebrae. Methods: From January 2023 to December 2023, a patient diagnosed with invasive hemangioma of the thoracic vertebra was admitted to the Second Department of Spine of the Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical University and voluntarily underwent surgical treatment. The patient was treated with the surgical technique of "percutaneous vertebroplasty + extractor of vertebral canal space occupying lesion under foraminoscope", and the outcome indicators of the patient were recorded 1 day before surgery, 1 week after surgery and more than 3 months after surgery, including VAS pain score, Lovett scale and imaging findings. The clinical efficacy of combined minimally invasive surgery for invasive hemangioma of thoracic vertebrae was determined by comparing the above observation indexes with self-before-after comparison. Results: One week after surgery, thoracic MRI scan + enhancement showed that about 60% of intraspinal hemangioma was removed, and the intraoperative area exudated obviously. The results of 4-month postoperative follow-up and 1-week postoperative review showed that the hemangioma that was not completely removed in the spinal canal gradually shrank, no significant recurrence or increase was observed, the spinal cord recovered significantly under compression, and the operative area exudated and fully absorbed, the VAS score of low back pain was 0/10, and the muscle strength of the right lower limb recovered to grade 4 +. Conclusion: Combined minimally invasive surgery provides a new idea for the minimally invasive treatment of invasive hemangioma of thoracic vertebrae, and the therapeutic effect is good.