体质对单髁置换术疗效影响的荟萃分析
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吕梁市人民医院

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Body constitution on the efficacy and safety of unicompartmental knee arthroplasty : A meta-analysis
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lvliangshirenminyiyuan

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    摘要:

    摘要:[目的]探讨体质对单髁置换术的疗效的影响及安全性分析。[方法]计算机检索建库至 2023 年 9 月中国知网、万方、维普、中国生物医学文献数据库、PubMed、Embase、Cochrane Library、Web Of Science 等,使用 RevMan 5.4 对纳入文献进行荟萃分析。[结果]共纳入11篇文献,各研究样本量为41-1000不等,其中前瞻性研究3篇,回顾性研究8篇,均为高质量研究。荟萃分析结果显示,肥胖组术后翻修率高于正常组 [I2=23%,RR=1.51,95%CI:1.06~2.14]。正常组OKS评分[I2=89%,MD=-2.99,95%CI:-5.18~-0.81]、关节活动度[I2=34%,MD=-3.38,95%CI:-4.32~-2.44]略优于肥胖组。肥胖组和正常组在VAS评分[I2=0,MD=-0.16,95%CI:-0.45~0.13]、KSS评分[I2=0,MD=-0.32,95%CI:-1.77~1.12]、HSS评分[I2=0,MD=-0.53,95%CI:-2.26~-1.21]、术后并发症[I2=3%,RR=1.78,95%CI:0.56~5.70]的差异均无统计学意义。[结论]正常组术后OKS评分、关节活动度略优于肥胖组。肥胖组术后翻修率增加,应在术前对患者进行减肥指导。综合看来,肥胖患者行单髁置换术有益。

    Abstract:

    [Objective]To investigate the efficacy and safety of body constitution on unicompartmental knee arthroplasty. [Methods] The database was searched to September 2023 from CNKI, Wanfang, VIP, China Biomedical Literature Database, PubMed, Embase, Cochrane Library, and Web Of Science. A meta-analysis of the included literature was performed using RevMan 5.4. [Results] A total of 11 articles were included, with sample sizes ranging from 41 to 1000. Among them, 3 were prospective studies and 8 were retrospective studies, all of which were high-quality studies. The meta-analysis results showed that the postoperative revision rate in the obese group was higher than that in the normal group [I2=23%, RR=1.51,95% CI: 1.06-2.14]. The OKS score [I2=89%, MD=-2.99, 95% CI: -5.18-0.81] and joint range of motion [I2=34%, MD=-3.38, 95% CI: -4.32-2.44] in the normal group were slightly better than those in the obese group. There was no statistically significant difference between the obese group and the normal group in VAS score [I2=0, MD=-0.16,95% CI: -0.45-0.13], KSS score [I2=0, MD=-0.32,95% CI: -1.77-1.12], HSS score [I2=0, MD=-0.53,95% CI: -2.26-1.21], and postoperative complications [I2=3%, RR=1.78,95% CI: 0.56-5.70]. [Conclusion] The OKS score and range of motion of the normal group were slightly better than those of the obese group. The rate of postoperative revision in the obese group increased, and patients should be given weight loss guidance before surgery. Overall, unicompartmental knee arthroplasty is beneficial for obese patients.

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  • 收稿日期:2023-11-01
  • 最后修改日期:2023-12-27
  • 录用日期:2024-03-22
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