Abstract:[Objective] To compare the clinical outcomes of total hip arthroplasty (THA) through the Orthopadische Chirurgie Munchen (OCM) approach versus the direct lateral approach (DLA). [Methods] A retrospective study was performed on 53 patients who received THA in our hospital from January 2018 to January 2022. According to the results of preoperative doctor-patient communication, 18 patients had THA performed through OCM approach,while the other 35 patients took DLA approach. The perioperative period, follow-up and imaging da- ta were compared between the two groups. [Results] All patients in both groups had THA completed successfully without nerve or vascular injury and other serious complications. Although the OCM group spend significantly longer operation time than the DLA group (P<0.05), the former proved significantly superior to the latter in terms of incision length, intraoperative blood loss, blood transfusion rate, postoperative time of getting out of bed and hospital stay (P<0.05). As time went during follow-up lasted for (15.0±3.2) months on an average, the Harris score and hip extension-flexion range of motion (ROM) significantly increased in both groups (P<0.05). There were no significant differences in preoperative Harris score and ROM between the two groups (P>0.05), which in the OCM group were significantly superior to those in the DLA group one month after surgery (P<0.05), whereas became not statistically significant between the two groups 3 months after surgery and at the latest follow-up (P>0.05). Radiographically, the acetabular abduction angle, anteversion angle and bilateral leg length discrepancy were not statistically significant between the two groups postoperatively (P>0.05). [Conclusion] Compared with the traditional DLA, the OCM approach used in THA has the advantages of less injury, less bleeding and faster postoperative recovery.