Abstract:In the surgical treatment of some spinal diseases, the active lumbar must be partially fixed and fused to stabilize the lumbosa- cral structure. The special physiological and anatomical structure of the lumbosacral region determines that the sacrum is the stress concen- tration area of the internal fixation system. Therefore, the failure of internal fixation often occurs on the sacral side first, and eventually leads to fusion failure, which seriously affects the clinical efficacy. With the development of imaging technology and the deepening of sacral biome- chanics research, the second sacral alar screw (S2AIS) has attracted more and more attention of spine surgeons because it increases fixation points and strengthens in the sacrum fixation without crossing the sacroiliac joint to avoid the related complications of sacroiliac fixation. This paper reviews the researches at home and abroad on the anatomy, biomechanics, technical points and clinical applications of S2AIS tech- nique in recent years, providing a reference for orthopedic surgeons and researchers.