糖尿病对后路腰椎间融合术预后的影响

Impact of diabetes mellitus on the prognosis of posterior lumbar interbody fusion

摘要:

既往研究显示，糖尿病作为一种全身代谢性疾病与后路腰椎间融合术 （posterior lumbar interbody fusion, PLIF） 的预后密切相关，其具体机制尚不明确。虽然有相关文献提示糖尿病患者 PLIF 术后并发症发生率高，但是通过有效控制围手术期的血糖，保证血糖的稳定性，评估患者的身体状况，糖尿病患者能够获得良好的手术疗效。本文旨在通过回顾以往文章，总结糖尿病患者行 PLIF 术全身、围手术期及远期并发症，探讨并完善糖尿病患者预测术后并发症的指标，分析糖尿病影响 PLIF 预后的机制，以期进一步评估 PLIF 手术的有效性和安全性，为临床医师提供参考。

Abstract:

Previous studies have shown that diabetes mellitus, a systemic metabolic disease, is closely related to the prognosis of posteri- or lumbar interbody fusion (PLIF), whereas the specific mechanism remains unclear. Although relevant literatures suggest that diabetic pa- tients have a high incidence of postoperative complications after PLIF, they could also obtain good surgical outcomes by effectively evaluat- ing patients' physical condition and controlling perioperative blood glucose to ensure it stability. The purpose of this article is to summarize the systemic and perioperative complications, as well as other long-term adverse role diabetes on PLIF by reviewing previous articles, to ex- plore and improve the parameters for predicting postoperative complications in diabetes patients, to analyze the mechanisms by which diabe- tes affects prognosis, and to evaluate the effectiveness and safety of PLIF under this condition to provide a reference for clinician.