Abstract:[Objective] To evaluate the outcomes of the video-assisted discharge education (VADE) program for intervention of kinesio- phobia after total knee arthroplasty (TKA). [Methods] One hundred and twenty patients who were undergoing TKA in our hospital from Octo- ber 2022 to May 2023 were included into this study, and divided into two groups using the random number table method, including 60 pa- tients in the video-assisted discharge education program (the video group) and 60 patients in the conventional discharge education program (the conventional group). The clinical data of the two groups were compared. [Results] All patients in both groups received corresponding dis- charge educations completely without statistically significant differences in age, sex, disease duration, and BMI between the two groups (P> 0.05). The VAS and Tampa scale for kinesiophobia significantly decreased (P<0.05), while the knee extension- flexion range of motion (ROM) and HSS score significantly increased in both groups over time (P<0.05). Th video group proved significantly superior to the conven- tional group in terms of VAS score [(0.9±0.9) vs (1.4±0.6), P<0.05], ROM [(119.5±7.0)° vs (115.5±7.5)°, P<0.05], HSS score [(85.7±3.3) vs (84.4±3.3), P<0.05], and Tampa score [(31.8±3.5) vs (33.3±3.2), P<0.05] one month postoperatively, despite of insignificant differences in abovementioned items before operation and 24 hours postoperatively between the two groups (P>0.05). [Conclusion] The video-assisted dis- charge education program does effectively reduce the degree of postoperative TKA kinesiophobia, relieve pain during the rehabilitation peri- od, improve knee function and knee extension-flexion mobility, and enhance patients' postoperative satisfaction.