骨质疏松全膝置换围手术期干预的现状△

Current status of perioperative intervention for osteoporosis in total knee arthroplasty

摘要:

骨质疏松症 （osteoporosis, OP） 与膝关节骨性关节炎 （knee osteoarthritis, KOA） 是危害中老年骨骼健康的疾病，同时罹患这两种疾病的患者数量庞大，此类患者行全膝关节置换术 （total knee arthroplasty, TKA） 存在手术治疗难度大，术后疼痛、假体松动、假体周围骨折、翻修风险增加等并发症，严重影响患者生活质量，因此医生与患者都需要意识到这两种疾病的严重危害，对 OP 合并 KOA 的患者进行评估，判断患者 OP 的严重程度，通过早期的用药，降低骨量的进一步丢失，维持良好的骨骼状态。

Abstract:

Osteoporosis (OP) and knee osteoarthritis (KOA) are the common diseases that harm the bone health in the middle-aged and elderly, and usually occurred concomitantly in a large number of patients. Total knee arthroplasty (TKA) in such patients become difficult with increased risks of complications, such as postoperative pain, prosthetic loosening, periprosthetic fracture, with an increased chance of revision, which seriously affect the quality of life of patients. Therefore, both doctors and patients need to be aware of the serious harm of OP and KOA comorbidity to evaluate the severity of OP in patients with KOA, and to reduce the further loss of bone mass and maintain good bone condition by early medication.