镁支架在骨组织工程中应用现状△

Current application of magnesium scaffolds in bone tissue engineering

摘要:

镁拥有与人体骨骼相似的机械性能，在生理环境中镁离子是人体必需的微量元素，它能在人体内以安全和可控的方式降解和吸收。因此，镁支架被视为具有良好生物相容性和可生物降解的支架备选材料之一。随着制造工艺的不断发展，多孔镁合金支架有望成为一种最有前途的支架替代材料。本综述涵盖了对镁支架的性能、制备技术、表面改性、合金化和生物学特性的研究进展。此外，还讨论了镁支架的应用、挑战和未来发展趋势。

Abstract:

Magnesium has similar mechanical properties to human bones, and magnesium ion is an essential trace element in the physi- ological environment, which can be degraded and absorbed in a safe and controlled manner in the human body. Therefore, magnesium are considered as one of the candidate materials for implant with good biocompatibility and biodegradation. With the continuous development of manufacturing technology, porous magnesium alloy is expected to become the most promising alternative material for making scaffold im- plant. This review covers the research progress on the properties, preparation techniques, surface modification, alloying and biological prop- erties of magnesium scaffolds. In addition, applications, challenges and future trends of the magnesium implant are discussed.