Abstract:[Objective] To compare the clinical outcomes of percutaneous repair with suture anchors versus open counterpart for treat-ment of acute Achilles tendon rupture. [Methods] A retrospective study was done on 35 patients who received surgical repair for acuteAchilles tendon rupture in our hospital from October 2017 to October 2021. According to the preoperative doctor-patient communication,16 patients underwent percutaneous repair of the tendon with suture anchor (the percutaneous group), while the remaining 19 patient under-went conventional open repair (open group). The perioperative and follow-up documents were compared between the two groups. [Results]All patients had corresponding surgical procedures performed successfully. The percutaneous group was significantly superior to the opengroup in terms of operation time [(56.6±10.4) min vs (81.7±28.7) min, P=0.003], incision length [(1.9±0.6) cm vs (7.7±3.5) cm, P<0.001], in-traoperative blood loss [(10.6±6.0) ml vs (26.0±15.8) ml, P<0.001], hospital stay [(8.2±1.6) days vs (11.1±3.5) days, P=0.015], but there wasno statistical significance in the walking time and incision healing grade between the two groups (P>0.05). The follow-up period lasted for(21.8±7.1) months in a mean, and the percutaneous group resumed full weight-bearing activity significantly earlier than the open group[(8.4±1.0) weeks vs (12.8±3.1) weeks, P=0.005]. The VAS, AOFAS and ATRS scores, as well as plantar flexion-dorsal extension ROM weresignificantly improved in both groups over time (P<0.05). Percutaneous group was significantly better than that of the open group in VASscore at 1 month [(1.6±0.4) vs (2.3±0.7), P=0.001] and 6 months postoperatively [(0.9±0.3) vs (1.3±0.4), P=0.005], despite of insignificantdifferences in terms of AOFAS, ATRS scores and plantar flexion-dorsal extension ROM between the two groups at any time points accord-ingly (P>0.05). [Conclusion] Compared with traditional open repair, percutaneous repair with suture anchor is less invasive, and more ben-eficial to functional recovery.