经皮椎体成形术后再发骨折的研究进展△

Research progress on refractures after percutaneous vertebroplasty

摘要:

骨质疏松症是骨科的常见疾病，老年人群中发生率较高。发生骨质疏松后，由于骨强度降低和骨脆性增加，日常活动中即可导致椎体压缩骨折，即骨质疏松性椎体压缩性骨折 （osteoporotic vertebral compression fracture, OVCF）。经皮椎体成形术 （percutaneous vertebroplasty, PVP） 是临床医生用于 OVCF 治疗的有效手段，但经过临床研究发现，PVP 术后容易再发椎体骨折，增加患者病痛和负担。其发展进程引起了骨科医生的重视，越来越多的学者对其发生原因及机制进行了相关研究。本文对近年来国内外关于 OVCF 患者 PVP 术后再发骨折的流行病学、时间和空间性、相关危险因素的相关研究进行综述，为临床工作提供参考，以减少 PVP 术后再发骨折的概率。

Abstract:

Osteoporosis is a common orthopedic disease with a high incidence in the elderly population. The vertebral compression fracture, also known as osteoporotic vertebral compression fracture (OVCF), occurs in daily activities due to decreased bone strength and in- creased bone fragility after osteoporosis. Percutaneous vertebroplasty (PVP) is an effective method for OVCF, but clinical studies have found that recurrent vertebral fractures might happened secondary to PVP, with increasing the pain and burden of patients. These phenome- na have attracted the attention of orthopedic clinicians, and more and more scholars have studied the causes and mechanisms of its occur- rence. In this paper, the epidemiology, temporal and spatial characteristics, and related risk factors of recurrent fractures after PVP for OVCF in recent years were reviewed, so as to provide references for clinical workers to reduce the probability of recurrent fractures after PVP.