Abstract:[Objective] To compare clinical efficacy of supramalleolar osteotomy (SMOT) with plate internal fixation (IF) versus external fixation (EF) by distracting Ilizarov frame for traumatic ankle varus deformity (TAVD) in adolescents. [Methods] A retrospective analysis was performed on 30 adolescent patients with TAVD treated in our hospital from February 2015 to February 2022. According to doctor-patient communication, 16 patients had SMOT with IF of anatomical plate, while other 14 patients were treated with SMOT with EF of distracting Ilizarov frame. The perioperative, follow-up and imaging data of the two groups were compared. [Results] The IF group proved significantly superior to the EF group in terms of operation time [(90.0±11.6) min vs (102.1±9.1) min, P=0.004] and hospital stay [(13.3±4.4) days vs (18.5±5.3) days, P=0.007], whereas significantly inferior to the EF group in terms of intraoperative blood loss [(156.9±46.7) ml vs (90.7± 14.4) ml, P<0.001], total incision length [(14.5±2.3) cm vs (4.6±0.8) cm, P<0.001], and postoperative ambulation time [(71.7±16.7) days vs (5.6±2.3) days, P<0.001]. The mean follow-up period lasted for (20.6±3.5) months on an average, and the VAS and AOFAS scores in both groups were significantly improved over time (P<0.05). Morever, the IF proved significantly better than the EF group regarding VAS score 6 months postoperatively [(1.3±1.3) vs (2.6±1.6), P=0.023]. Regarding image, talus title (TT), tibial anterior surface angle (TAS), and Takakura scale were significantly improved in both groups after surgery compared with those preoperatively (P<0.05). The IF group was significantly superior to the EF group in terms of TAS [(89.8±1.4)° vs (87.6±3.4)°, P=0.036] and Takakura grade [0/I/II/IIIa/IIIb/IV, (2/11/3/0/0/0) vs (0/7/ 6/1/0/0), P=0.038] 3 months after surgery. [Conclusion] Both fixation methods in SMOT are effective in the treatment of juvenile TAVD.Compared with internal fixation, the external fixation has advantages of less surgical trauma, less bleeding, early weight-bearing activities, avoiding bone grafting, etc., whereas it has disadvantages such as longer operation time, longer hospital stay, more intraoperative fluoroscopy, and greater pain for patients.