Abstract:[Objective] To investigate the clinical outcomes of lateral biportal arthroscopic calcaneal spur resection and plantar fascia release for heel pain. [Methods] A retrospective study was conducted on 58 patients who received treatment for heel pain in our hospital from January 2017 to October 2022. Based on the doctor-patient discussion before treatment, 29 patients underwent the arthroscopic surgery (the surgical group), while other 29 patients received conservative treatment (the conservative group). The documents regarding to treatment period, follow-up and images were compared between the two groups. [Results] All the 29 patients in the surgical group were successfully operated on without neurovascular injury, incision infection and other complications. On other hand, those in the conservative group had no adverse reactions during the therapeutic period. During the follow-up period lasted for more than 1 year, no adverse phenomenon or symptom recurrence happened in anyone of the surgery group, whereas heel pain recurred in 2 cases in the conservative group at 6 and 12 months later respectively, who got symptoms were relieved after conservative treatment again. The VAS, AOFAS and Maryland scores in both groups improved significantly over time (P<0.05). There were no significant differences in VAS, AOFAS and Maryland scores between the two groups before treatment (P>0.05). However, the surgical group proved significantly superior to the conservative group in terms of VAS score [(3.1± 1.1) vs (5.2±1.2), P<0.001; (1.6±0.8) vs (4.6±1.4), P<0.001; (0.6±0.6) vs (3.9±1.3), P<0.001], AOFAS score [(73.9±10.4) vs (52.2±14.1), P< 0.001; (86.1±5.6) vs (59.0±13.3), P<0.001; (93.5±2.9) vs (62.4±13.0), P<0.001] and Maryland score [(73.9±10.8) vs (53.0±14.0), P<0.001; (86.1±5.5) vs (59.3±12.5), P<0.001; (93.3±2.6) vs (63.0±13.4), P<0.001] 3, 6 and 12 months after treatment. With regard to imaging, the post-operative X-rays showed that calcaneal spur disappeared, and no recurrence of calcaneal spur occurred until the last follow-up in all the 29 patients in the surgical group, whereas the spurs revealed in images remained unchanged in all patients of the conservative group over time. [Conclusion] The lateral biportal arthroscopic calcaneal spur resection and plantar fascia release for heel pain have the advantage of good curative effect with less iatrogenic trauma. It is superior to conservative treatment in preventing recurrence of heel pain.