3D打印半骨盆重建肿瘤切除后缺损

3D printed semi-pelvis reconstruction for defect secondary to tumor resection

摘要:

[目的] 评价 3D 打印半骨盆重建骨盆的安全性及早期临床疗效。[方法] 回顾性分析 2022 年 1 月—2023 年 4 月本科收治的 12 例骨盆肿瘤患者的临床资料，评价围手术期情况及短期随访结果。[结果]12 例患者均顺利完成手术，手术时间平均（339.3±97.1）min，术中出血量平均（956.3±708.8）ml，术中输注悬浮红细胞量平均（4.5±3.0）u，术中输注新鲜冰冻血浆平均（412.5±359.4）ml。随访时间平均（7.2±4.0）个月。1 例患者术后 7 个月因肿瘤进展死亡，1 例术后 1 年发生假体脱位，经手术进行复位。与术前相比，末次随访时，疼痛 VAS 评分 [(3.3±0.5), (2.0±0.7), P=0.014] 显著减少，髋关节 Harris 评分 [(46.7±5.4), (64.8±7.3), P=0.003] 、MSTS 评分 [(11.0±4.8), (16.3±2.9), P＜0.001] 显著增加。[结论] 通过 3D 打印半骨盆重建可有效减轻患者疼痛，功能较术前恢复，是一种安全有效的重建方法。

Abstract:

[Objective] To evaluate the safety and early clinical efficacy of 3D printed semi-pelvis reconstruction for defect secondary to tumor resection. [Methods] A retrospective study was done on 12 patients who received semi-pelvis reconstruction with 3D printed prostheses for pelvic tumor in our department from January 2022 to April 2023. The documents regarding to perioperative conditions and shortterm follow-up results were evaluated. [Results] All the 12 patients were successfully operated, with an average operation time of (339.3± 97.1) min, intraoperative blood loss of (956.3±708.8) ml, the intraoperative suspended red blood cell infusion of (4.5±3.0) units, and intraoperative plasma infusion of (412.5±359.4) ml. All of them were followed up for (7.2±4.0) months on an average, 1 patient died 7 months after surgery due to tumor progression, and 1 patient suffered dislocation 1 year after surgery and underwent surgical reduction. Compared with those preoperatively, pain VAS score significantly decreased at the last follow-up [(3.3±0.5), (2.0±0.7), P=0.014], whereas the Harris hip score [(46.7±5.4), (64.8±7.3), P=0.003], the MSTS score [(11.0±4.8), (16.3±2.9), P＜0.001] significantly increased. [Conclusion] The semipelvis reconstruction with 3D printed prostheses does effectively reduce the pain, and improve the function postoperatively, which is a safe and effective reconstruction method.