Abstract:[Objective] To compare the clinical efficacy of suture combined fixation versus steel wire combined fixation for comminuted fractures of the patellar inferior pole. [Methods] A retrospective study was done on 52 patients who received surgical treatment for comminuted fractures of the patellar inferior pole in our hospital from January 2019 to December 2021. According to preoperative surgeon-patient discussion, 28 patients were treated with suture combined fixation (the suture group), while other 24 patients underwent steel wire combined fixation (the wire group). The perioperative, follow-up and imaging documemts were compared between the two groups. [Results] All patients had corresponding surgical procedures performed successfully, with no serious complications occurred during the operation. Although there were no significant differences in the total incision length, intraoperative blood loss and incision healing grade between the two groups (P>0.05), the suture group proved significantly superior to the wire group in terms of operation time [(60.7±7.8) mim vs (67.0±8.8) min, P=0.009], intraoperative fluoroscopy times [(2.2±0.5) times vs (4.3±0.8) times, P<0.001], pain VAS score 5 days postoperatively [(4.5± 0.9) vs (5.5±0.8), P<0.001], postoperative walking time [(2.2±0.6) days vs (3.0±0.7) days, P<0.001] and hospital stay [(7.9±0.9) days vs (8.6± 1.3) days, P=0.015]. The follow-up period lasted for (18.3±3.8) months in a mean, and the suture group resumed full weight-bearing activity significantly earlier than the wire group [(10.9±3.1) weeks vs (12.7±2.5) weeks, P=0.031]. The VAS score for anterior knee pain, knee range of motion (ROM), Bostman and Kujala scores significantly improved in both groups over time (P<0.05), which in the suture group were significantly superior to those in the wire group (P<0.05), except Bostman score between two groups at 3 months after surgery and the latest follow-up (P>0.05). As for imaging, there were no significant changes in Insall-Salvati index and patella length in both groups over time (P>0.05). At all corresponding time points, the suture group had significantly less Insall-Salvati index (P<0.05), while significantly greater patellar length than the wire group (P<0.05), additionally, the former got fracture healing significantly earlier than the latter (P< 0.05). [Conclusion] The vertical interrupt sutures with Nice knot fixation combined with suture anchor takes benefits of shorter operation time, faster recovery, less complications and no need for a second operation to remove implant over the steel wire counterpart for fixation of comminuted fractures of the patellar inferior pole.