Abstract:[Objective] To compare the clinical outcomes of hip hemiarthroplasty versus internal fixation with proximal femoral nail an-ti-rotation (PFNA) for femoral intertrochanteric fractures in the elderly. [Methods] A retrospective study was conducted on 128 elderly pa-tients who received surgical treatment for femoral intertrochanteric fractures in our hospital from August 2015 to August 2020. According tothe preoperative doctor-patient communication, 66 patients received hip hemiarthroplasty (the hemiarthroplasty group), while other 62 pa-tients received PFNA fixation (the PFNA group). The documents regarding to perioperative period, follow-up and images were compared be-tween the two groups. [Results] Although the hemiarthroplasty group proved significantly greater than the PFNA group in terms of operativetime [(62.9±5.2) min vs (52.5±4.9) min, P<0.001], total incision length [(15.1±0.8) cm vs (12.2±0.8) cm, P<0.001], intraoperative blood loss[(301.8±40.9) ml vs (142.9±20.2) ml, P<0.001], and length of hospital stay [(13.7±1.1) days vs (12.6±1.5) days, P<0.001], the former wassignificantly better than the latter in intraoperative fluoroscopy times [(3.5±1.1) times vs (13.8±2.1) times, P<0.001] and the ambulationtime [(3.4±1.3) days vs (18.0±4.6) days, P<0.001]. In addition, the hemiarthroplasty group regained full weight bearing activity significantlyearlier than the PFNA group [(24.0±2.0) days vs (59.4±2.6) days, P<0.001]. The VAS score and Harris score significantly improved in bothgroups over time (P<0.05), and the hemiarthroplasty group was significantly superior to the PFNA group in terms of VAS score at all timepoint after surgery (P<0.05), and Harris scores at 1 and 3 months after operation (P<0.05). With respect of imaging, the leg length discrep-ancy in the hemiarthroplasty group significantly reduced at the last follow-up compared with that before surgery. On other hand, the femoralneck shaft angle (FNSA) significantly decreased (P<0.05), whereas the tip-apex distance (TAD) significantly increased in the PFNA groupat the last follow-up compared with those immediately after operation (P<0.05). [Conclusion] Both hemiarthroplasty and PFNA fixationachieve satisfactory consequences for femoral intertrochanteric fractures in the elderly. In comparison, hemiarthroplasty is more advanta-geous as long as the patient's own conditions permit before surgery.