Abstract:[Objective] To present the medium-term clinical outcome of pedicled iliac flap combined with cannulated screw fixationfor displaced femoral neck fractures in middle-age adult. [Methods] A retrospective study was performed on 19 middle-aged patients whounderwent pedicled iliac flap combined with cannulated screw fixation for displaced femoral neck fractures from January 2014 to Septem-ber 2020. The clinical and imaging data were evaluated. [Results] All patients were successfully operated on, with operation time of (129.3±9.8) min, incision length of (16.7±1.7) cm, intraoperative blood loss of (50.5±6.7) ml, and the hospital stay of (10.1±1.0) days. All of themwere followed up for the average of (60.1±7.8) months, and regained full weight-bearing activity in a mean of (12.2±4.3) weeks. Comparedwith those 1 month after surgery, VAS scores [(3.1±1.8) vs (1.5±2.3), P=0.015], hip flexion-extension ROM [(113.3±7.3)° vs (129.2±8.3)°,P=0.018], hip internal-external rotation ROM [(76.3±3.2)° vs (89.5±2.7)°, P<0.001], Harris score [(79.4±2.3) vs (90.6±4.6), P=0.024] sig-nificantly improved by the time of the latest follow-up. Radiologically, the mean fracture healing time was (4.5±6.7) months in an average.Compared with those 1 month after surgery, Garden index remained unchanged at the last follow-up (P>0.05), whereas the Tonnis scale fordegeneration significantly deteriorated (P<0.05), with femoral head necrosis in 2 cases (GardenⅣ type) more than 2 years after fracturehealing. [Conclusion] Pedicled iliac flap combined with cannulated screw fixation does achieve satisfactory clinical consequence for dis-placed femoral neck fractures in middle-age adult.