Abstract:[Objective] To investigate the clinical efficacy of 3D printing assisted planning Ortho-Bridging system for personalized fixa-tion of femoral intertrochanteric fractures. [Methods] A retrospective research was done on 46 patients who had intertrochanteric fracturefixed with bridging system planned individually by 3D printing from January 2017 to September 2021. The clinical and imaging documentswere evaluated. [Results] All patients were successfully operated, with the average operation time of (78.3±16.2) min, intraoperative bloodloss of (210.2±113.3) ml, and hospital stay of (13.1±5.0) d, and followed up for more than 12 months. Compared with those 3 months postop-eratively, the pain VAS score significantly declined [(2.1±0.9), (1.4±0.5), P＜0.001], whereas Harris score [(77.3±3.5), (87.5±3.2), P＜0.001]and hip flexion-extesion range of motion (ROM) [(89.9±6.4)°, (124.3±7.9)°, P＜0.001] increased significantly at the latest fullow-up. Imag-ing, compared with those preoperatively, the fracture alignment significantly improved [excellent/good/can/poor, (0/2/3/41), (15/24/6/1), (14/25/5/2), P＜0.001], shaft-neck angle increased significantly 3 months postoperatively and the latest follow-up [(93.7±3.9)°, (128.3±5.4)°,(126.2±5.2)°, P＜0.001]. All the patients got fracture healing at the latest follow-up. [Conclusion] This 3D printing assisted planning Ortho-Bridging system for fixation of femoral intertrochanteric fractures has satisfactory short-term consequence, which is conducive to personal-ized treatment.