Abstract:[Objective] To evaluate the clinical efficacy of discectomy under delta large channel endoscope in the treatment of lumbardisc herniation. [Methods] A retrospective study was conducted on 73 patients who received the large-channel endoscopic discectomy forlumbar disc herniation from January 2020 to October 2021. The clinical and imaging data were evaluated. [Results] All the patients weresuccessfully operated with the average operative time of (78.1±24.0) min, intraoperative fluoroscopy of (3.3±1.0) times, and followed up for(18.2±5.3) months. Compared with those preoperatively, back pain VAS [(5.6±1.8), (1.8±1.0), (1.1±0.9), P<0.001], leg pain VAS score [(7.5±1.5), (1.3±1.0), (1.1±0.8), P<0.001], ODI [(70.3±15.7), (15.2±10.3), (7.6±6.0), P<0.001], JOA score [(10.3±3.3), (20.9±2.0), (23.8±3.3), P<0.001] significantly improved 3 months postoperatively and at the last follow-up. Radiographically, the lumbar lordosis remained unchangedat the last follow-up compared with that before surgery (P>0.05), but the intervertebral disc height index increased significantly [(26.6±4.9)%, (28.2±5.2)%, P<0.001]. [Conclusion] The delta endoscopy achieves generally satisfactory consequences in the treatment of lumbardisc herniation, and is a minimally invasive surgical method.