Abstract:[Objective] To investigate the clinical efficacy of Lando? double-layer artificial dermis used for repair of finger tip defectcomplicated with bone exposed. [Methods] From January 2020 to December 2022, 30 patients (30 fingers) had double-layer artificial der-mis with pressure dressing used after debridement to repair the finger tip defect complicated with bone exposed. The compression suture kitwas removed 7~10 days after surgery, the sutures were removed 3 weeks after surgery, while the surface silicone film over double layer arti-ficial dermis was removed 4 weeks after surgery to allow the wound to be naturally epithelialized. The appearance of wound healing andfunctional recovery were observed, and the curative effect was evaluated. [Results] Of the 30 patients, 27 patients got wound healing in onestage, 2 patients had a part of the wound remained without bone exposure, and got wound healed after dressing change, whereas one patientremained a part of the tendon exposure after surgery, and had the tendon healed after revision double-layer artificial dermis implantation.All the patients were followed up for more than 6 months, with the mean time of natural epithelialization of (60.1±8.8) days. After the woundhealed, the finger belly was well-stacked with good color and proper skin sensation. Compared with that 3 months after surgery, the averagetwo-point discrimination was significantly improved at 6 months after surgery [(3.8±1.1) mm, (2.5±0.9) mm, P＜0.001]. [Conclusion] Thisdouble-layer artificial dermis used to repair of finger tip defect with bone exposed in one stage is simple and effective technique without do-nor area damage.