Abstract:[Objective] To compare the clinical outcomes of arthroscopic surgery versus open counterpart for glenohumeral dislocationcomplicated with avulsion fracture of the humeral greater tubercle. [Methods] A retrospective study was done on 80 patients who receivedsurgical treatment for glenohumeral dislocation combined with avulsion fracture of humeral greater tubercle from May 2021 to February2022. According to the doctor-patient communication, 42 patients underwent arthroscopic reduction and double-row anchor suture bridgefixation (the arthroscopic group), while other 37 patients received open reduction and fixation with proximal humeral locking plate (opengroup). The perioperative period, follow-up and imaging data of the two groups were compared. [Results] Although the arthroscopic groupconsumed significantly longer operative time than the open group [(75.2±9.4) min vs (62.5±9.3) min, P<0.001], the former proved signifi-cantly superior to the latter in terms of intraoperative blood loss [(28.5±7.5) ml vs (85.1±8.5) ml, P<0.001], total length of incision [(1.3±0.6)cm vs (5.0±2.2) cm, P<0.001], active activity time [(3.1±0.9) weeks vs (3.9±0.9) weeks, P<0.001] and hospital stay [(8.3±1.2) days vs (9.6±1.6) days, P<0.001] and incidence of postoperative complications (0% vs 18.9%, P=0.010). As time went by after surgery, the VAS, ASESand Constant-Murley scores, as well as anterior flexion, abduction and external rotation ROMs were significantly improved in both groups(P<0.05). At 3, 6 and 12 months after surgery, the arthroscopic group were significantly better than the open group in terms of abovemen-tioned items (P<0.05). With respect of imaging, the arthroscopic group was also superior to the open group in fracture reduction quality [ex-cellent/good/fair/poor, (25/17/1/0) vs (18/12/5/2), P=0.036]. At 3 months and 12 months after surgery, the arthroscopic group had significant-ly less subacromial interval (SAI) than the open group (P<0.05). [Conclusion] Minimally invasive shoulder arthroscopy achieves better clin-ical consequences than the traditional open surgery in the treatment of glenohumeral dislocation complicated with avulsion fracture of hu-meral greater tubercle.