Abstract:[Objective] To explore the impact of facet symmetry on clinical consequence of percutaneous endoscopic transforaminal discectomy (PETD) for prolapsed lumbar disc herniation. [Methods] A retrospective study was conducted on 30 patients who had prolapsed lumbar disc herniation treated with PETD, including 20 patients with symmetrical bilateral facets (SBF), and 10 patients with asymmetric bilateral facets (ABF) from September 2022 to September 2023. The clinical and imaging data of the two groups were compared. [Results] There were no significant differences in operation time, intraoperative fluoroscopy times, ambulation time and hospital stay between the two groups (P>0.05). All patients were followed up for more than 3 months. As time went on, the lower back pain VAS, leg pain VAS, ODI and JOA scores in both groups were significantly improved (P<0.05). The SBF group proved significantly superior to the ABF group in term of lower back pain VAS scores [(2.7±1.3) vs (6.8±1.2), P<0.001; (1.7±0.7) vs (3.8±0.6), P<0.001] 1 day postoperatively and at the last followup. As for imaging, the intervertebral space height and vertebral canal area in both groups were significantly increased at the last follow-up compared with those preoperatively (P<0.05). At the last follow-up, the SBF group was also significantly better than the ASF group regarding to intervertebral space height [(10.7±1.8) mm vs (7.0±1.8) mm, P<0.001]. [Conclusion] PETD is effective treatment for prolapsed lumbar disc herniation. However, the patients with preoperative asymmetry bilateral facets will last longer postoperative symptoms of low back pain.