Abstract:[Objective] To evaluate the clinical outcome of arthroscopic single-bundle reconstruction of anterior cruciate ligament (ACL) and meniscus suture in the treatment of ACL rupture complicated with medial meniscus buck-handle tear (BHT). [Methods] A retrospective research was done on 38 patients had ACL rupture combined with medial meniscus BHT treated surgically by abovementioned technique from May 2017 to May 2020. The clinical and imaging data were evaluated. [Results] All the patients had operation performed successfully without any serious complications such as vascular and nerve injury, whereas with the average operation time of (93.0±35.6) min, and were followed up for (2.0±0.4) years in a mean. Compared with those preoperatively, the VAS score [(6.4±1.8), (0.4±0.6), P< 0.001], and 2000 IKDC score [(37.0±20.3), (94.3±4.8), P<0.001], Lysholm score [(41.7±23.8), (95.0±3.9), P<0.001], knee extension-flexion range of motion (ROM) [(97.7±28.5)°, (130.8±11.0)°, P<0.001] were significantly improved at the latest follow-up. In addition, the anterior drawer test [1+/2+/3+, (0/0/21/17), (38/0/0/0), P<0.001], Lachman tests [1+/2+/3+, (0/0/21/17), (38/0/0/0), P<0.001], pivot shift test [negative/weakly positive/positive, (21/9/8), (0/38/0), P<0.001] were significantly improved correspondingly. The second arthroscopic look 2 years after operation revealed the meniscus completely healed in 18 cases (47.3%), partially healed in 12 cases (31.6%), and not healed in 8 cases (21.1%). [Conclusion] The arthroscopic single-bundle ACL reconstruction and meniscus suture do alleviate knee pain and improve knee function for ACL rupture complicated with medial meniscus buck-handle tear, with meniscus healed completely or partially in 30 of 38 cases.