Abstract:[Objective] To review the consequence of arthroscopic release and progressive rehabilitation for knee ankylosis secondary to cruciate ligament reconstruction. [Methods] From January 2020 to December 2023, 201 patients received arthroscopic knee cruciate ligament reconstruction in our hospital. Among them, 16 patients developed knee stiffness, underwent revision arthroscopic release, and progressive rehabilitation, involving continuous passive motion (CPM), active closed chain and open chain knee excises on the basis of adequate analgesia. The clinical data of the 16 patients were evaluated. [Results] All the 16 patients underwent arthroscopic release smoothly without iatrogenic fracture, whereas with operative time of (60.5±10.5) min and blood loss of (50.0±8.8) mL. As time elapsed preoperatively, 1 month postoperatively and last follow-up lasted for (15.0±3.5) months, the knee ROM [(102.0±1.2), (120.4±4.4), (134.0±1.5), P＜0.001], VAS score [(4.0±0.5), (3.6±0.6), (1.2±0.2), P＜0.001], Lysholm score [(43.0±1.6), (73.4±1.8), (88.3±1.9), P＜0.001], IKDC scores [(47.5± 1.8), (69.3±2.0), (86.2±1.4), P＜0.001] and KSS score [(44.0±1.8), (73.7±1.8), (88.0±1.5), P＜0.001] were significantly improved. [Conclusion] Arthroscopic release and progressive rehabilitation exercise do effectively treat knee adhesion after cruciate ligament reconstruction and achieve satisfactory functional recovery.