Abstract: [Objective] To search the factors related to clinical outcomes of open reduction and internal fixation (ORIF) combined with arthroscopic repair for distal radius fracture complicated with triangular fibrocartilage complex (TFCC) tear. [Methods] A retrospective research was done on 152 patients who had distal radius fractures complicated with triangular fibrocartilage complex (TFCC) tear treated by ORIF and arthroscopic repair in Dezhou Branch Qilu Hospital, Shandong University from 2021 to December 2023. Based on GartlandWerley wrist score at the last follow-up, the patients were divided into good group and poor group. Univariate comparison and logistic multivariate regression analysis were conducted to analyze the factors related to the clinical outcome. [Results] The 152 patients were comprehensively marked in term of clinical results at the latest follow-up, 120 (79.0%) patients fall into the good group, while the remaining 32 (21.0%) were into the poor group. The good group proved significantly younger than the poor group in term of age [(58.8±10.2) years vs (65.3±9.8) years, P=0.002]. In addition, the former had significantly less complexity in term of Palmar classification than the latter group [IA/IB/IC/ID/compound, (17/53/1/39/10) vs (3/6/1/5/17), P<0.001]. Moreover, the good group was significantly greater than the poor group regarding the preoperative ulnar inclination [(19.4±2.0)° vs (15.0±1.9)°, P<0.001] and volar tilt [(-10.6±2.6)° vs (-13.2±2.5)°, P<0.001]. However, there were no significant differences in terms of gender, BMI and ASA scale, as well as smoking, drinking, hypertension, diabetes, liver disease, kidney disease history, and interval from injury to operation, radial styloid height, operation time, TFCC repair method, and postoperative fixation time between the two groups (P>0.05). As results of multiple logistic regression, the advanced age (OR=9.219, P= 0.002) and complex Palmar classification (OR=2.024, P<0.001) were risk factors for poor clinical outcomes, while greater ulnar inclination (OR=0.302, P<0.001) and greater volar tilt (OR=0.665, P<0.001) were protective factors for poor outcomes. [Conclusion] Age, Palmar clas-sification, preoperative ulnar inclination and volar tilt are the main factors affecting surgical outcome of distal radius fracture complicated with TFCC tear, and targeted intervention aiming the abovesaid factors is needed to improve the therapeutic consequece and promote functional recovery. distal radius fracture, triangular fibrocartilage complex injury, open reduction and internal fixation, wrist arthroscopy, influencing factors