Abstract:[Objective] To compare the clinical outcomes of total hip arthroplasty (THA) through minimal incision posterolateral ap- proach versus conventional posterolateral approach. [Methods] All randomized or non- randomized controlled trials about THA through minimal incision versus conventional posterolateral approaches were searched from PubMed, Cochrane Library, EMbase, Web of Science, CNKI and Wanfang database from January 2003 to July 2021. After screening and data extraction were conducted according to inclusion and exclusion criteria, a meta-analysis was performed using RevMan 5.3 software. [Results] A total of 14 literatures were included, involv- ing 2 randomized controlled trials and 12 cohort studies. As results of the meta-analysis, the minimal incision group proved significantly su- perior to the conventional group in terms of incision length (SMD=- 3.78, 95% CI:-4.97~- 2.58, P<0.001) , intraoperative blood loss (SMD=-2.27, 95% CI: -3.13~-1.40, P<0.001) , postoperative drainage (SMD=- 6.90, 95% CI: -7.57~-6.23, P<0.001) , complications (OR=0.34, 95% CI: 0.21~0.56, P<0.001) , abducent angles (SMD=-0.24, 95%CI: -0.41~ -0.06, P=0.007) , hospital stay (SMD= -1.93, 95% CI: -2.33~-1.52, P<0.001) and Harris hip score at 6 months after surgery (SMD=0.87, 95% CI: 0.34~1.40, P=0.001) . However, there were no significant differences between the two groups in terms of operation time (SMD=0.50, 95% CI: -0.20~1.19, P=0.16) and VAS score (SMD=-0.51, 95% CI: -1.31~0.29, P=0.21) . [Conclusion] This study shows that the clinical outcome of THA through minimal incision posterolateral approach is considerably better than that of conventional posterolateral approach.