Abstract:[Objective] To investigate the clinical efficacy of anterior cervical discectomy and fusion (ACDF) for cervical spondylosis accompanied by vertigo, and the correlation between the vertigo and cervical imaging parameters. [Methods] A retrospective study was done on 32 patients who received ACDF for cervical spondylosis complicated with vertigo in our hospital from July 2017 to July 2019. The relationships between vertigo and imaging parameters were analyzed. [Results] All patients had surgical procedures completed successful- ly, and followed up for (28.45±2.87) months on an average. At the last follow-up, the DHI score, JOA score, and NDI score were significant- ly improved compared with those before surgery (P<0.05) . Radiographically, C2~7 lordosis angle, intervertebral space height, and spinal ca- nal area significantly improved postoperatively compared with those before surgery (P<0.05) , with the average distraction height of the in- tervertebral space of 119.3% compared with the baseline height. As result of correlation analysis, the pre-postoperative variation of DHI score proved significantly positively correlated to pre-postoperative variation of spinal canal area (P<0.05) . [Conclusion] ACDF surgery does effectively treat cervical spondylosis accompanied with vertigo, with moderately expanded height of the intervertebral space, and in- creased cervical curvature. However, the improvement of vertigo symptoms is positively correlated with the increase of spinal canal area.