Abstract:[Objective] To explore the short-term outcomes of two kinds of decompression and fixation for radioulnar fractures compli- cated with early-stage compartment syndrome. [Methods] From March 2015 to June 2020, 60 patients underwent surgical treatment for ra- dioulnar fractures complicated with early-stage compartment syndrome. According to doctor-patient communication, 29 patients received decompression combined with double plate fixation (DPF group) , while the remaining 31 patients received decompression combined with radial plate and ulnar intramedullary nail fixation (the hybrid group) . The clinical and imaging data of the two groups were compared. [Results] The hybrid group proved significantly superior to the DPF in terms of incision length, operation time, periosteal dissection area, intra- operative blood loss, postoperative drainage, wound closure time and hospital stay (P<0.05) . The VAS scores significantly decreased over time at early stage after surgery in both groups (P<0.05) , which in the hybrid group were significantly better than those of the DPF group at 3 and 5 days after surgery (P<0.05) . The patients were followed up for (13.18±1.63) months on an average, and the hybrid group was signifi- cantly superior to the DPF group in terms of forearm pronation-supernation range of motion (ROM) and DASH scores at 6 months after sur- gery (P<0.05) . Radiographically, the hybrid group got fracture healing significantly earlier than the DPF group (P<0.05) . [Conclusion] Compared with double plate, the hybrid fixation is more effective for treatment of radioulnar fractures accompanied with early-stage com- partment syndrome.