Abstract:[Objective] To evaluate the clinical outcomes of bone cement augmented proximal femoral nail anti-rotation (PFNA) for in- ternal fixation of osteoporotic femoral intertrochanteric fractures. [Methods] A retrospective study was conducted on 99 patients who re- ceived surgical treatment for osteoporotic femoral intertrochanteric fractures from June 2016 to June 2020. Based on doctor-patient commu- nication, 42 patients received cement-augmented PFNA fixation, while the other 57 patients underwent hip hemiarthroplasty (HA) . The perioperative, follow-up and imaging data were compared between the two groups. [Results] All the patients in both groups had correspond- ing surgical procedures performed successfully without serious complications, with no significant differences in terms of operative time, inci- sion healing, postoperative ambulation time and hospital stay between the two groups (P>0.05) . As time went during the follow up lasted for (24.52±8.65) months on an average, the VAS score decreased significantly (P<0.05) , whereas the Harris score, hip flexion-extension range of motion (ROM) , and internal-external rotation ROM significantly increased in both groups (P<0.05) . However, there were no significant differences in abovesaid items between the two groups at any matching time points (P>0.05) . In addition, there was no a significant differ- ence in the time to resume full-weight bearing activity between the two groups (P>0.05) . Radiographically, there were no statistically signif- icant differences in femoral shaft angle, femoral head offset, or femoral length compared with the healthy side between the two groups at the latest follow up (P>0.05) . [Conclusion] This cement-augmented PFNA fixation of osteoporotic femoral intertrochanteric fractures is benefi- cial to the early recovery of walking and weight-bearing activities, and achieves the clinical outcomes similar to the HA.