Abstract:[Objective] To compare the short-term clinical outcomes of femoral neck system (FNS) versus inverted cannulated cancel- lous screw (ICCS) for femoral neck fractures. [Methods] A retrospective study was done on 73 patients who received internal fixation for femoral neck fracture from January 2018 to March 2021. According to preoperative doctor-patient communication, 33 patients were treated with FNS, while the remaining 40 patients were with ICCS. The perioperative, follow-up and imaging results were compared between the two groups. [Results] All the patients in both groups were operated on successfully without neurovascular injury and other serious complica- tions. Although there were no significant differences in operative time, total incision length, intraoperative blood loss and hospital stay be- tween the two groups (P>0.05) , the FNS group proved significantly superior to the ICCS group in terms of intraoperative times of fluorosco- py and postoperative ambulation time (P<0.05) . The follow-up period lasted for (17.91±3.63) months on an average, and the FNS group re- sumed full- weight-bearing activity significantly earlier than the ICCS group (P<0.05) . The VAS scores decreased significantly (P<0.05) , while the hip extension and flexion range of motion (ROM) , hip internal and external rotation ROM, and Harris score significantly in- creased in both groups over time after surgery (P<0.05) . The FNS group was significantly superior to the ICCC group in terms of VAS score at the latest follow up (P<0.05) , and Harris score at all corresponding time points postoperatively (P<0.05) . Radiographically, there was no a statistically significant difference in Garden alignment index between the two groups postoperatively (P>0.05) , but FNS proved signifi- cantly superior to ICCS group in terms of fracture healing time and femoral neck shortening (P<0.05) . In addition, there were no significant differences between the two groups in terms of neck-shaft angle, T?nnis hip osteoarthritis grade, as well as incidences of bone nonunion, in- ternal fixation failure and femoral head necrosis (P>0.05) . [Conclusion] The FNS for internal fixation of femoral neck fracture takes the ad- vantages of strong fixation stability, good recovery of hip function and fast fracture healing.