Abstract:Upper cervical cellular schwannoma is more likely to occur in the patients aged 40 to 50 years, but its incidence is extreme- ly low. The clinical symptoms are atypical with no obvious symptoms of spinal cord compression in the early stage, whereas often radicular irritation, and lack of obvious imaging features. This tumor is difficult to be distinguished from cervical spondylosis and malignant peripher- al nerve sheath tumors, prone to be misdiagnosed and mistreated. Once discovered, the disease should be surgically treated actively, which is the only and most effective treatment way currently. The surgical methods involve hemilaminectomy, en block vertebral resection, intra- capsular resection, and microsurgery techniques. The surgical consequences are usually good with satisfactory overall clinical outcomes. A reasonable surgical plan should be made based on various factors, such as different imaging manifestations, tumor invasion, functional needs, and stability after cervical surgery.