Abstract:[Objective] To compare the short- and medium-term clinical outcomes of anterior cruciate ligament (ACL) reconstruction with remnant preservation by suture anchor versus conventional ACL reconstruction without remnant preservation. [Methods] A retrospec- tive study was conducted on 51 patients who underwent arthroscopic ACL reconstruction from March 2019 to March 2021. According to pre- operative doctor-patient communication and intraoperative arthroscopic findings of ACL remnant, 25 patients received ACL reconstruction combined with remnant preservation (RP) by suture anchor tightening, while the other 26 patients had the conventional (CV) ACL recon- struction performed only due to poor remnant quality. The perioperative period, follow-up and imaging results were compared between the two groups. [Results] All the 51 patients underwent corresponding surgical procedures successfully without vascular or nerve injury. Al- though the RP group consumed significantly longer operation time than the CV group (P<0.05) , the former returned postoperative ambula- tion significantly earlier than the latter (P<0.05) . All the patients in both groups were followed up for (13.35±1.18) months on an average, and the RP group resumed full weight-bearing activity significantly earlier than the CV group (P<0.05) . The pivot shift test and Lachman test significantly improved (P<0.05) , while the Lysholm and IKDC 2000 scores significantly increased in both groups over time (P<0.05) , regardless of no significant change in passive angle regeneration of the knee (P>0.05) . At 3 months after operation, the RP group proved significantly superior to the CV group in terms of Lysholm and IKDC 2000 scores, as well as passive angle regeneration test (P>0.05) , whereas which became not statistically significant at 6 months and 12 months after operation (P>0.05) . Radiographically, there was no sig- nificant difference in the excellent rate of femoral and tibial tunnel location between the two groups (P>0.05) . At 3 months after operation the RP group was significantly superior to the CV group in term of bone tunnel enlargement (P<0.05) , but there was no significant differ- ence in bone tunnel enlargement and Kellgren- Lawrence grade between the two groups at 6 months and 12 months after operation (P> 0.05) . [Conclusion] Compared with the conventional ACL reconstruction, the remnant-preserving ACL reconstruction does achieve better knee function and proprioceptive recovery in short-term.