Abstract:[Objective] To compare the clinical outcomes of all anterior 2 portals in figure-4 position versus conventional 3 portals for location of tibial tunnel in arthroscopic posterior cruciate ligament (PCL) reconstruction. [Methods] A retrospective study was conducted on a total of 83 patients who received arthroscopic PCL reconstruction in our hospital from April 2018 to December 2020. According to the re- sults of preoperative doctor-patient communication, 29 patients had the tibial tunnel located by the 2-portal technique, while the remaining 54 patients were by the conventional 3-portal technique. The documents regarding to perioperative period, follow-up and radiographs were compared between the two groups. [Results] All the patients in both groups had PCL reconstructed successfully without serious complica- tions, such as neurovascular injuries. The 2-portal group proved significantly superior to the 3-portal group in terms of operation time, total incision length and intraoperative blood loss (P<0.05) , although there was no significant difference in the times of fluoroscopy, postopera- tive walking time, incision healing and hospital stay between the two groups (P>0.05) . In addition, there was no a significant difference in the time to return to full weight-bearing activity between the two groups (P>0.05) . The VAS, Lysholm, and IKDC scores improved signifi- cantly (P<0.05) , whereas knee extension-flexion range of motion (ROM) remained unchanged over time in both groups (P>0.05) . The pos- terior stability revealed by posterior drawer test at 90° of knee flexion significantly improved in both groups at 6 months postoperatively and the latest follow-up compared with those preoperatively (P<0.05) . However, there were no significant differences in VAS, Lysholm, and IK- DC scores, as well as knee ROM and consequence of posterior drawer test between the two groups at the corresponding time points (P> 0.05) . Radiographically, there were no significant differences in sagittal, coronal and axial position data of the internal opening of the tibial tunnel between the two groups (P>0.05) . The Kellgren-Lawrence grade for osteoarthritis remained unchange over time in the two groups (P>0.05) . [Conclusion] There is no significant difference in the location of the tibial tunnel between all anterior 2-portal technique in fig- ure-4 position and conventional 3-portal method in posterior cruciate ligament reconstruction. By contrast, the former has considerably less iatrogenic trauma than the latter.