载瘤骨段液氮灭活回植的应用现状

Current clinical application of liquid nitrogen-treated tumor-bearing bone

摘要:

骨的恶性肿瘤目前多采用保肢术治疗，以尽可能保留肢体功能。肿瘤切除后造成的骨缺损，多采用假体重建或者生物型重建。近年来，液氮灭活载瘤骨回植重建，因其操作简单、灭活彻底、骨愈合率高等优点，而成为有广泛应用前景的生物重建技术。该技术目前在日本及欧美应用较多，我国开展较少。本文就液氮灭活载瘤骨重建骨缺损在骨恶性肿瘤保肢术中的应用及进展作一综述。

Abstract:

Limb salvage surgery is more and more popularly used to treat malignant tumors of bone, in order to preserve limb function as much as possible. The bone defect secondary to tumor resection is usually reconstructed by prostheses or bioactive materials. In recent years, replantation of liquid nitrogen treated tumor-bearing bone has become a widely used biological reconstruction technique due to its advantag- es of simple operation, complete inactivation and high bone healing rate. At present, the technology is widely applied in Japan and Europe and America, while seldomly used in China. This article reviews the progress of bone defect reconstruction by replantation of liquid-nitrogen treated tumor-bearing bone in limb salvage surgeries for bone malignant tumors.