Abstract:[Objective] To compare the clinical outcomes of modified Ma-Griffith percutaneous repair (PR) versus conventional openrepair (OR) of acute closed Achilles tendon rupture. [Methods] A retrospective study was conducted on 72 patients who received surgicaltreatment for acute closed Achilles tendon rupture in our hospital from July 2015 to February 2020. Based on the results of doctor-patientcommunication, 38 patients underwent PR, while the other 34 patients received conventional open repair (OR). The perioperative periodand follow-up data of the two groups were compared. [Results] The PR group proved significantly superior the OR group in terms of opera-tion time [(45.5±5.9) min vs (49.0±7.0) min, P<0.05], the total length of incision [(5.5±0.8) cm vs (7.9±0.9) cm, P<0.05], intraoperativeblood loss [(16.1±4.1) ml vs (25.9±4.9) ml, P<0.05], postoperative ambulation time [(4.0±1.6) days vs (7.0±1.7) days, P<0.05], incision heal-ing grade [A/B/C, (38/0/0) vs (30/4/0), P<0.05] and hospital stay [(8.2±1.9) days vs (12.0±2.5) days, P<0.05]. The PR group got significantlyhigher incidence of sural nerve injury than the OR group (20.1% vs 2.9%, P<0.05), whereas the former had significantly lower incidence ofpostoperative incision infection than the latter (0.0% vs 11.8%, P<0.05). All patients were followed up for a mean of (15.9±2.8) months, andthe PR group resumed full weight-bearing activity significantly earlier than the OR group [(59.3±4.7) days vs (87.8±4.4) days, P<0.05]. TheVAS score decreased significantly (P<0.05), while AOFAS score and ankle range of motion (ROM) increased significantly in both groupsover time postoperatively (P<0.05). The PR group proved significantly superior to the OR group in terms of VAS score [(1.9±0.6) vs (3.9±0.8), P<0.05], AOFAS [(86.0±3.4) vs (74.7±5.0), P<0.05], ATRS score [(89.2±4.0) vs (77.2±4.0), P<0.05] and ankle ROM [(48.7±3.6)° vs(39.7±4.1)°, P<0.05] 1 month postoperatively, whereas which became not statistically significant between the two groups at the latest followup (P>0.05). [Conclusion] Compared with open repair, the percutaneous repair, a minimally invasive surgery, does significantly reduce theinfection rate after Achilles tendon rupture and improve the early postoperative functional recovery, despite of higher risk of sural nerve in-jury.