氢氧混合气对肩袖损伤术后早期的影响△

Effect of hydrogen-oxygen mixture inhalation on early consequences of arthroscopic repair of rotator cuff tear

摘要:

[目的] 探讨氢氧混合气对肩袖损伤术后早期肩关节功能的影响。[方法] 回顾性分析2020 年2 月—2021 年10 月60 例行单侧肩关节镜下肩袖修补术的患者。依据术前医患沟通结果，30 例术后吸入氢氧混合气（氢氧组）， 30 例术后吸入纯氧气（纯氧组）。比较两组临床结果与检验资料。[结果] 患者均顺利完成手术，两组手术时间、插管30 min 后平均动脉压及心率变化差异无统计学意义（P＞0.05）。所有患者均完成12 周随访，随时间推移，术后两组VAS 评分、UCLA 和Constant-Mur-ley 评分均显著改善（P＜0.05）。术前两组上述评分的差异均无统计学意义（P＞0.05），术后12 周，氢氧组VAS 评分[(1.7±0.6)vs (2.2±0.7), P＜0.05]、UCLA [(29.1±0.8) vs (28.3±1.5), P＜0.05] 以及Constant-Murley 评分[(93.7±2.1) vs (91.4±3.9), P＜0.05] 均显著优于纯氧组。检验方面，两组患者术后血清IL-6 及TNF-a 水平均显著降低（P＜0.05）。术后12 周，氢氧组的IL-6 [(1.5±0.8) pg/ml vs (2.2±0.3) pg/ml, P=0.040] 和TNF-α [(2.0±0.9) pg/ml vs (2.6±0.9) pg/ml, P=0.026] 均显著低于纯氧组。[结论] 术后吸入氢氧混合气可以缓解肩关节镜术后肩关节痛疼，改善肩关节功能。

Abstract:

[Objective] To explore the effect of hydrogen -oxygen mixture inhalation on early consequences of arthroscopic repair of ro-tator cuff tear. [Methods] A retrospective study was performed on 60 patients who underwent unilateral arthroscopic rotator cuff repair fromFebruary 2020 to October 2021. According to the preoperative doctor-patient communication, 30 patients were inhaled hydrogen and oxy-gen mixture (the HOM group), while other 30 patients were inhaled pure oxygen (the PO group). The clinical and blood test data of the twogroups were compared. [Results] All patients were operated on successfully, without significant differences in the operation time, mean arte-rial pressure and heart rate 30min after intubation between the two groups (P＞0.05). As all patients were followed up for 12-weeks, theVAS score for pain, Constant-Murley and UCLA scores in both groups were significantly improved over time (P＜0.05). Although there wasno statistical significance in the above scores between the two groups before surgery (P＞0.05), the HOM group proved significantly superiorto the PO group 12 weeks after surgery in terms of VAS score [(1.7±0.6) vs (2.2±0.7), P＜0.05], UCLA [(29.1±0.8) vs (28.3±1.5), P＜0.05] andConstant-Murley score [(93.7±2.1) vs (91.4±3.9), P＜0.05]. Regarding blood test, the levels of serum IL-6 and TNF-a in both groups weresignificantly decreased after surgery (P＜0.05). The HOM group was significantly lower than the PO group in terms of IL-6 [(1.5±0.8) pg/mlvs (2.2±0.3) pg/ml, P=0.040] and TNF-alpha [(2.0±0.9) pg/ml vs (2.6± 0.9) pg/ml, P=0.026] 12 weeks postoperatively. [Conclusion] Inhala-tion of hydrogen and oxygen mixture does relieve pain and improve function after arthroscopic repair of rotator cuff tear.