骨骼肌损伤微波热疗机制的研究进展△

Research progress in the mechanism of microwave hyperthermia for skeletal muscle injury

摘要:

骨骼肌损伤（Skeletal muscle injury, SMI） 作为人类运动训练当中最常见的症状，会严重影响患者的生活质量，给社会医疗保障体系带来巨大的负担。而微波热疗广泛用于各种临床和运动康复环境中，对骨骼肌损伤具有明显的的治疗效果，但微波热疗对骨骼损伤的治疗机制尚未完全阐明。目前研究表明，微波热疗与骨骼肌中热休克蛋白的表达、骨骼肌生长发育时的分子机制以及骨骼肌损伤发生后的氧化应激反应相关，但微波热疗缺乏量化标准。本文针对微波治疗骨骼肌损伤的蛋白、细胞以及分子机制进行综述，为临床医生更好地实施微波热疗提供理论依据。

Abstract:

Skeletal muscle injury (SMI), as the most common event in human sports training, seriously affects the quality of life of pa-tients and brings a huge burden to the social medical security system. Microwave hyperthermia is widely used in a variety of clinical andsports rehabilitation environments, and has obvious therapeutic effect on skeletal muscle injury, but the therapeutic mechanism of micro-wave hyperthermia on skeletal injury has not been fully understood. Current studies have shown that microwave hyperthermia plays role inthe expression of heat shock proteins in skeletal muscle, involving the molecular mechanism of skeletal muscle growth and development andoxidative stress after skeletal muscle injury, despite lack of quantitative standard about microwave hyperthermia effect. This article reviewsthe protein, cellular and molecular mechanisms of microwave treatment for skeletal muscle injury, in order to provide a theoretical basis forclinicians to better implement microwave hyperthermia.