Abstract:[Objective] To evaluate the clinical outcomes of Tinavi orthopedic robot assisted pedicle screw fixation with increasing ce-phalic tilting in the fractured segment for thoracolumbar fractures. [Methods] A retrospective study was performed on 60 patients who re-ceived percutaneous pedicle screw fixation for single-segment thoracolumbar fractures with upper endplate collapse in our hospital fromAugust 2018 to June 2021. According to preoperative doctor-patient communication, 25 patients received robot-assisted pedicle screwplacement with increasing cephalic tilting in the fractured segment, while the other 35 patients received routine fluoroscopy-guidancescrew placement. The clinical and imaging data of the two groups were compared. [Results] All patients had operations performed success-fully without serious complications. The robot group proved significantly superior to the routine group in terms of operative time [(90.8±3.4)min vs (93.6±4.5) min, P<0.05] and intraoperative blood loss [(96.4±8.6) ml vs (115.7±23.6) ml, P<0.05]. The VAS scores in both groupswere significantly decreased over time (P<0.05), which were not significant different between the two groups at any time points accordingly(P>0.05). Regarding imaging, the robot group was significantly better than the routine group in term of Gertzbein-Robbins scale of screw in-sertion accuracy [A/B/C, (138/2/0) vs (174/20/2), P<0.05]. Compared with those preoperatively, the relative vertebral height and local ky-photic Cobb angle of injured vertebra significantly improved in both groups postoperatively (P<0.05). The robot group was significantly bet-ter than the routine group regarding to the relative height of the injured vertebra [(27.0±2.2) mm vs (21.9±4.1) mm, P<0.05] and local ky-photic Cobb angle [(7.8±2.1)° vs (10.2±2.6)°, P<0.05] 3 months after surgery. [Conclusion] For thoracolumbar fracture with upper endplatecollapse, fractured-segment pedicle screw placement with increasing cephalic tilting under Tinavi orthopaedic robot does achieve betterclinical consequences.