Abstract:[Objective] To introduce the surgical technique and preliminary clinical results of free flap and bone transportation withTaylor spatial frame (TSF) for bone and soft tissue defects around the ankle. [Methods] A total of 16 patients were surgically treated forbone and soft tissue defects around the ankle from January 2016 to February 2020. In the first stage, complete debridement was performedto remove infected and necrotic bone and soft tissue, temporary fixation was performed with a simple external fixation frame, and the defectwound was covered with vacuum sealing drainage (VSD). In the second stage, according to the wound site, area, soft tissue defect and vascu-lar condition, the free lat dorsal myocutaneous flap, anterolateral femoral myocutaneous flap and medial gastrocnemius myocutaneous flapwere used to repair the soft tissue defect. After the survival of the flap, the bone transportation or tibiotalars fusion with TSF were performedat the third stage according to the extent of bone defects. During the last operation, TSF was installed and fixed according to the require-ments of treatment with osteotomy. One week after the surgery, an electronic prescription was made according to the deformity, installationand frame parameters measured before surgery. The bone transportation with TSF were adjusted at a rate of 1 mm/d per day, divided intofour times, and finally distraction osteogenesis and tibial talus fusion were completed. [Results] All the 16 patients were followed up for 14~52 months, with external frame wearing time of (17.3±2.4) months, the bone healing of (14.8±1.4) months, and the total treatment time of(17.9±2.2) months. At the last follow-up, total tibial lengthening was of (7.5±1.1) cm. The clinical outcome was marked as excellent in 12cases and good in 4 cases based on AOFAS criteria. [Conclusion] Free flap and bone transportation with Taylor spatial frame can effective-ly repair bone and soft tissue defects around the ankle, with high success rate of tibiotalar fusion, good recovery of alignment and successfulreconstruction of lower limb function.