Abstract:[Objective] To introduce the surgical technique and preliminary clinical outcomes of posterior atlantoaxial anti-rotationscrew rod fixation for atlantoaxial dislocation. [Methods] From June 2018 to June 2022, 16 patients underwent abovesaid surgical proce-dures for reversible atlantoaxial dislocation. As posterior midline incision was performed under general anesthesia, the pedicle screws or par-tial transpedicle screws were placed on the C1, while pedicle screws or laminar screws were placed on the C2. Subsequently, the pre-curvedanti-rotation rods were installed to construct the atlanto-axial anti-rotation screw rod system for lifting, reducing and fixing C1~C2. Finally il-iac autogenous bone graft was implanted for C1~C2 fusion. After operation, the atlantoaxial reduction, fusion, and neurological function wereevaluated in regular intervals. [Results] All the 16 patients had the operation completed successfully with no complications, such as nerveand vascular injury. The patients got symptoms improved significantly after surgery, with satisfactory atlantoaxial reduction on images. TheADI decreased from (5.7±1.3) mm before surgery to (1.7±0.7) mm one week after surgery, whereas the JOA score increased from (13.7±1.1)before surgery to (16.3±0.9) one week after surgery. At the latest follow-up lasted from 3 to 24 months, all patients achieved atlanto-axialbony fusion. [Conclusion] The posterior atlantoaxial instrumented fusion with this anti-rotation screw-rod system for atlantoaxial disloca-tion does achieve satisfactory short-term clinical consequence with an advantage of more convenient surgical operation. However, furthercomparison with the conventional atlantoaxial screw system is needed to verify its advantages.