Abstract:[Objective] To investigate the effect of lateral wall reconstruction on postoperative stability of femoral intertrochanteric frac-tures. [Methods] One elderly female volunteer was selected to obtain the femoral CT data. Medical 3D software was used to construct themodel of intertrochanteric fracture and proximal femoral nail anti-rotation (PFNA) with intact lateral wall (the intact group), lateral wall de-fect (defect group), and lateral wall reconstructed by plate (reconstruction group). Boundary conditions and constraint conditions were set,and different loads were applied to the femoral head to analyze Von Mises stress, displacement and strain of the femor-PFNA system. [Results] The displacement femor-PFNA system was slightly larger in the intact group and defect group than that of reconstruction group,whereas which were not statistically significant between any two of the three groups (P>0.05). The Von Mises stress was not significantly dif-ferent in the mean maximum stress between any two of the three model groups under different stress loads (P>0.05). The maximum mainstrain was ranked in the order of reconstruction group > intact group > defect group, which in the reconstructed group was significantly high-er than that of the defect group [(30.3±15.1)×10-3 vs (22.5±12.1)×10-3, P<0.001], while there was no significant difference between the re-constructed group and the defect group in the mean maximum PFNA strain (P>0.05). [Conclusion] Lateral wall reconstruction can improvethe overall stability of the femor-PFNA system, reduce the stress distribution of the femor-PFNA system, and increase the strain distribu-tion of the proximal femur.