Abstract:[Objective] To search the related factors of rotator cuff retear after repair and establish and verify the prediction model.[Methods] A total of 92 patients with large rotator cuff tear admitted to our hospital from January 2019 to October 2022 were selected as theresearch subject, all of whom were given the large rotator cuff tear repair, and the re-tear was observed within 12 months after surgery. Uni-variate comparison and logistic regression analysis were used to explore the factors related to retear, and the prediction model of retear aftersurgery was established and validated. [Results] Of the 92 patients, 21 were confirmed as postoperative rotator cuff retear, accounting for22.8%. As for univariate comparison, the re-tear group proved significantly greater than the healed group in terms of primary tear length[(4.1±0.6) cm vs (3.5±0.4) cm, P<0.001], the degree of tendon retraction [I/II/III, (7/10/4) vs (2/49/20), P=0.003], the degree of rotator cuff fatinfiltration [I/II/III, (10/8/3) vs (41/29/1), P=0.039], while the former was significantly less than the latter in terms of the acromiohumeral dis-tance (AHD) [(3.7±0.3) mm vs (4.1±0.4) mm, P<0.001], and tendon repair quality [1/2, (13/8) vs (59/12), P=0.039]. As results of logistic re-gression, poor tendon repair quality (OR=5.333, P<0.001), less AHD (OR=5.145, P<0.001), greater tendon retraction degree (OR=4.707, P<0.001), longer tear length (OR=4.384, P<0.001) were the risk factors for postoperative re-tear. The results of the nomogram prediction modelshowed that the C-index index was 0.809 (95%CI 0.763~0.841), and the correction curve for predicting retear after repair of giant rotatorcuff tear was close to the ideal curve (P>0.05). ROC curve results showed that the sensitivity, specificity and area under curve (AUC) of thenomogram model for predicting postoperative retear were 81.0%, 84.5%, and 0.856 (95%CI 0.776~0.939). [Conclusion] Tear length, ten-don retraction degree, acromiohumeral distance and tendon repair quality are risk factors for postoperative retear, and the nomogram modelis effective in predicting the risk of retear after repair of giant rotator cuff tear.